156586-89-9
Chemical Structure
Edrecolomab
Synonym(s): Panorex; CO17-1A
- CAS No.: 156586-89-9
- Formula:N/A
- Molecular Weight:(144.18 kDa)
IUPAC Name: 7-bromo-2,6-dichloro-5-fluoroquinazolin-4(3H)-one
SMILES: [Edrecolomab]
Biological Activity: Edrecolomab (Panorex) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A, expressed on epithelial tissues and on various carcinomas. Edrecolomab shows anti-tumor activity and can be used in colorectal carcinoma research[1][2].
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Edrecolomab | 99.90% | Edrecolomab (Panorex) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A, expressed on epithelial tissues and on various carcinomas. Edrecolomab shows anti-tumor activity and can be used in colorectal carcinoma research. | ||||||||||||||||||||
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- [1]. Naundorf S, et al. In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment. Int J Cancer. 2002 Jul 1;100(1):101-10. [Content Brief]
- [2]. Punt CJ, et al. Edrecolomab alone or in combination with fluorouracil and folinic acid in the adjuvant treatment of stage III colon cancer: a randomised study. Lancet. 2002 Aug 31;360(9334):671-7. [Content Brief]
Keywords