157946-92-4
157946-92-4
Chemical Structure
2'-Deoxy-8-methylthioguanosine
- CAS No.: 157946-92-4
- Formula:C11H15N5O4S
- Molecular Weight:313.33
IUPAC Name: 2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-(methylthio)-1,9-dihydro-6H-purin-6-one
InChIKey: BNMGNOHWLDCZKX-KVQBGUIXSA-N
SMILES: O[C@@H]1[C@@H](CO)O[C@@H](N2C(N=C(N)NC3=O)=C3N=C2SC)C1
Biological Activity: 2'-Deoxy-8-methylthioguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2'-Deoxy-8-methylthioguanosine | 2'-Deoxy-8-methylthioguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
