159439-02-8
159439-02-8
Chemical Structure
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
- CAS No.: 159439-02-8
- Formula:C32H46N5O17P
- Molecular Weight:803.70
IUPAC Name: ((S)-2-acetamido-3-(4-(phosphonooxy)phenyl)propanoyl)-L-glutamyl-L-glutamyl-L-isoleucyl-L-glutamic acid
InChIKey: QQEKQSBIEKQXQS-PSCZMIBCSA-N
SMILES: O=C(O)CC[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC1=CC=C(OP(O)(O)=O)C=C1)NC(C)=O)=O)=O)=O)=O
Biological Activity: Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].
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Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH | Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions. | |||||||||||||||||||||
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