159453-08-4
![[pTyr5] EGFR (988-993) Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-p1799.gif "[pTyr5] EGFR (988-993) Chemical Structure")
Chemical Structure
[pTyr5] EGFR (988-993)
- CAS No.: 159453-08-4
- Formula:C31H45N6O17P
- Molecular Weight:804.69
IUPAC Name: (2S,5S,8S,11S,14S,17S)-17-amino-8-(2-carboxyethyl)-11-(carboxymethyl)-2-isobutyl-14-methyl-4,7,10,13,16-pentaoxo-5-(4-(phosphonooxy)benzyl)-3,6,9,12,15-pentaazanonadecanedioic acid
InChIKey: KVTXKWFVCLLHQU-TVVJCWKZSA-N
SMILES: CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=C(OP(O)(O)=O)C=C1)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CC(O)=O)N)=O)=O)=O)=O)=O
Biological Activity: [pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B)[1].
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[pTyr5] EGFR (988-993) | [pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B). | |||||||||||||||||||||
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