1596348-16-1
Chemical Structure
KDM5-C49
Synonym(s): KDOAM-20
- CAS No.: 1596348-16-1
- Formula:C15H24N4O3
- Molecular Weight:308.38
IUPAC Name: 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid
InChIKey: RGGMVQDDHDCRDM-UHFFFAOYSA-N
SMILES: O=C(C1=CC=NC(CNCC(N(CC)CCN(C)C)=O)=C1)O
Biological Activity: KDM5-C49 (KDOAM-20) is a potent and selective inhibitor of KDM5 demethylases, with IC50s of 40 nM, 160 nM, and 100 nM for KDM5A, KDM5B, and KDM5C enzymes, respectively. KDM5-C49 can be used for the research of cancer[1].
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KDM5-C49 | KDM5-C49 (KDOAM-20) is a potent and selective inhibitor of KDM5 demethylases, with IC50s of 40 nM, 160 nM, and 100 nM for KDM5A, KDM5B, and KDM5C enzymes, respectively. KDM5-C49 can be used for the research of cancer. | |||||||||||||||||||||
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Keywords