160212-93-1
160212-93-1
Chemical Structure
HPV16 E7 (86-93)
- CAS No.: 160212-93-1
- Formula:C37H66N8O10S
- Molecular Weight:815.03
IUPAC Name: L-threonyl-L-leucylglycyl-L-isoleucyl-L-valyl-L-cysteinyl-L-prolyl-L-isoleucine
InChIKey: CEZGUHHOZXJLRF-ZWPFISNSSA-N
SMILES: CC[C@H](C)[C@@H](C(O)=O)NC([C@H]1N(C([C@H](CS)NC([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](CC(C)C)NC([C@H]([C@H](O)C)N)=O)=O)=O)=O)=O)=O)CCC1)=O
Biological Activity: HPV16 E7 (86-93) is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide. HPV16 E7 (86-93) is immunogenic in cervical carcinomas[1][2].
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HPV16 E7 (86-93) | HPV16 E7 (86-93) is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide. HPV16 E7 (86-93) is immunogenic in cervical carcinomas. | |||||||||||||||||||||
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References
- [1]. Cheng WF, et al. Induction of human papillomavirus type 16-specific immunologic responses in a normal and an human papillomavirus-infected populations. Immunology. 2005 May;115(1):136-49. [Content Brief]
- [2]. Hoffmann TK, et al. T cells specific for HPV16 E7 epitopes in patients with squamous cell carcinoma of the oropharynx. Int J Cancer. 2006 Apr 15;118(8):1984-91. [Content Brief]
