1612192-06-9
1612192-06-9
Chemical Structure
5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine
- CAS No.: 1612192-06-9
- Formula:C20H18ClFN4O5
- Molecular Weight:448.83
IUPAC Name: ((2R,3R,4R,5S)-4-acetoxy-5-(6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate
InChIKey: ZGDFADBOEZXSJY-ZLHSVIROSA-N
SMILES: F[C@H]1[C@H](OC(C)=O)[C@@H](N2C(N=CN=C3Cl)=C3N=C2)O[C@@H]1COC(C4=CC=C(C)C=C4)=O
Biological Activity: 5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine | 5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
