161258-30-6
Chemical Structure
Hexapeptide-11
- CAS No.: 161258-30-6
- Formula:C36H48N6O7
- Molecular Weight:676.80
InChIKey: GFEYWOGCSROPRT-OBXVVNIGSA-N
SMILES: O=C(O)[C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](C)NC([C@H](C(C)C)NC([C@H](CC4=CC=CC=C4)N)=O)=O)=O)CCC3)=O)=O)CCC1
Biological Activity: Hexapeptide-11 is an anti-aging peptide that can protect fibroblasts from premature cell senescence mediated by oxidative stress. Hexapeptide-11 is also a potential stimulator of hyaluronic acid in keratinocytes, and can enhance skin barrier function by upregulating the expression of HAS2 and EGR3, and downregulating the expression of HYAL2. Hexapeptide-11 can also improve skin elasticity[1][2][3].
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Hexapeptide-11 | 99.77% | Hexapeptide-11 is an anti-aging peptide that can protect fibroblasts from premature cell senescence mediated by oxidative stress. Hexapeptide-11 is also a potential stimulator of hyaluronic acid in keratinocytes, and can enhance skin barrier function by upregulating the expression of HAS2 and EGR3, and downregulating the expression of HYAL2. Hexapeptide-11 can also improve skin elasticity. | ||||||||||||||||||||
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References
- [1]. Sklirou AD, et al. Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts. Redox Biol. 2015 Aug;5:205-215. [Content Brief]
- [2]. Errante F, et al. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Front Chem. 2020;8:572923. [Content Brief]
- [3]. Widgerow AD, et al. Designing topical hyaluronic acid technology-Size does matter…. J Cosmet Dermatol. 2022 Jul;21(7):2865-2870. [Content Brief]
