161395-35-3
Chemical Structure
ABT-299
- CAS No.: 161395-35-3
- Formula:C32H28ClFN4O4S
- Molecular Weight:619.11
IUPAC Name: (R)-1-(acetoxymethyl)-3-(7-(1-(dimethylcarbamoyl)-6-(4-fluorophenyl)-1H-indole-3-carbonyl)-1H,3H-pyrrolo[1,2-c]thiazol-3-yl)pyridin-1-ium chloride
InChIKey: NKIONDJYXPXFFL-JSSVAETHSA-M
SMILES: CC(OC[N+]1=CC=CC([C@H]2SCC3=C(C=CN23)C(C4=CN(C5=C4C=CC(C6=CC=C(C=C6)F)=C5)C(N(C)C)=O)=O)=C1)=O.[Cl-]
Biological Activity: ABT-299 is a prodrug of a platelet-activating factor (PAF) antagonist that exhibits significant inhibitory activity on PAF-induced β-platelet globulin release in vitro after in vivo administration in humans, an effect that may be partially attributed to the pyridine-N-oxide metabolite.
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ABT-299 | ABT-299 is a prodrug of a platelet-activating factor (PAF) antagonist that exhibits significant inhibitory activity on PAF-induced β-platelet globulin release in vitro after in vivo administration in humans, an effect that may be partially attributed to the pyridine-N-oxide metabolite. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
