1628345-10-7
1628345-10-7
Chemical Structure
ARN14686
- CAS No.: 1628345-10-7
- Formula:C15H24N2O3
- Molecular Weight:280.36
IUPAC Name: undec-10-yn-1-yl (S)-(2-oxoazetidin-3-yl)carbamate
InChIKey: XEXRAYPXQNELAS-ZDUSSCGKSA-N
SMILES: O=C(OCCCCCCCCCC#C)N[C@H]1CNC1=O
Biological Activity: ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM). ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe[1].
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ARN14686 | ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM). ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe. | |||||||||||||||||||||
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