1629052-58-9
1629052-58-9
Chemical Structure
Martinostat
- CAS No.: 1629052-58-9
- Formula:C22H30N2O2
- Molecular Weight:354.49
InChIKey: WNIDBXBLQFPAJA-FQRVRAMHSA-N
SMILES: CN(CC(C=C1)=CC=C1/C=C/C(NO)=O)CC2(C[C@@H](C3)C4)C[C@@H]4C[C@@H]3C2
Biological Activity: Martinostat is a HDAC inhibitor and can be labeled with radionuclides for quantitative imaging of HDACs in vivo in the central nervous system and major peripheral organs[1][2].
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Martinostat | Martinostat is a HDAC inhibitor and can be labeled with radionuclides for quantitative imaging of HDACs in vivo in the central nervous system and major peripheral organs. | |||||||||||||||||||||
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References
- [1]. Changning Wang, et al. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs. J Med Chem. 2014 Oct 9;57(19):7999-8009. [Content Brief]
- [2]. Tharick A Pascoal, et al. [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease. Nat Commun. 2022 Jul 19;13(1):4171. [Content Brief]
