163769-88-8
163769-88-8
Chemical Structure
YM-90709
- CAS No.: 163769-88-8
- Formula:C22H21N3O2
- Molecular Weight:359.42
IUPAC Name: 2,3-dimethoxy-6,6-dimethyl-5,6-dihydrobenzo[7,8]indolizino[2,3-b]quinoxaline
InChIKey: HIXSPVQXXDULHS-UHFFFAOYSA-N
SMILES: CC(CC1=CC(OC)=C(OC)C=C12)(C)N3C2=CC4=NC5=CC=CC=C5N=C43
Biological Activity: YM-90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).YM-90709 potently inhibits the binding of [125I]-IL-5 to IL-5R on human peripheral eosinophils and eosinophilic HL-60 clone 15 cells with IC50 values of 1.0 and 0.57 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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YM-90709 | 99.20% | YM-90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).YM-90709 potently inhibits the binding of [125I]-IL-5 to IL-5R on human peripheral eosinophils and eosinophilic HL-60 clone 15 cells with IC50 values of 1.0 and 0.57 μM. | ||||||||||||||||||||
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Keywords
