1638885-65-0
1638885-65-0
Chemical Structure
Apalutamide-d4
Synonym(s): ARN-509-d4
- CAS No.: 1638885-65-0
- Formula:C21H11D4F4N5O2S
- Molecular Weight:481.46
IUPAC Name: 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl-1,1,3,3-d4)-2-fluoro-N-methylbenzamide
InChIKey: HJBWBFZLDZWPHF-NZLXMSDQSA-N
SMILES: O=C(NC)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43C([2H])([2H])CC4([2H])[2H])C=C1F
Biological Activity: Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].
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Apalutamide-d4 | 99.93% | Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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Apalutamide (Standard) | ≥98% | Apalutamide (Standard) is the analytical standard of Apalutamide. This product is intended for research and analytical applications. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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Apalutamide-13C,d3 | 99.90% | Apalutamide-13C,d3 is the 13C- and deuterium labeled Apalutamide. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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Apalutamide-d3 | Apalutamide-d3 is the deuterium labeled Apalutamide. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | |||||||||||||||||||||
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Apalutamide-d7 | Apalutamide-d7 is deuterated labeled Apalutamide (HY-16060). Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | |||||||||||||||||||||
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Apalutamide | 99.94% | Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM. | ||||||||||||||||||||
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References
