1643958-85-3
Chemical Structure
PDK1-IN-2
- CAS No.: 1643958-85-3
- Formula:C15H9ClN2O2S3
- Molecular Weight:380.89
IUPAC Name: N-(6-chlorobenzo[d]thiazol-2-yl)benzo[b]thiophene-3-sulfonamide
InChIKey: VLGMTYRMKMVUHJ-UHFFFAOYSA-N
SMILES: O=S(NC1=NC2=C(S1)C=C(Cl)C=C2)(C3=CSC4=C3C=CC=C4)=O
Biological Activity: PDK1-IN-2 is a small molecule inhibitor of 3-phosphoinositol-dependent protein kinase-1 (PDK1). PDK1-IN-2 inhibits the binding of PDK1 to its substrate by competitively binding to the PIF pocket of PDK1, thereby inhibiting the kinase activity and downstream signaling of PDK1. PDK1-IN-2 can be used for cell survival and proliferation in cancer[1].
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PDK1-IN-2 | 98.90% | PDK1-IN-2 is a small molecule inhibitor of 3-phosphoinositol-dependent protein kinase-1 (PDK1). PDK1-IN-2 inhibits the binding of PDK1 to its substrate by competitively binding to the PIF pocket of PDK1, thereby inhibiting the kinase activity and downstream signaling of PDK1. PDK1-IN-2 can be used for cell survival and proliferation in cancer. | ||||||||||||||||||||
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Keywords
