1644498-53-2
Chemical Structure
BI-9774
- CAS No.: 1644498-53-2
- Formula:C26H25ClN4O5S
- Molecular Weight:541.02
IUPAC Name: ((4'-(6-chloro-2-(((3R,3aR,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl)oxy)-1H-imidazo[4,5-b]pyridin-5-yl)-[1,1'-biphenyl]-4-yl)imino)dimethyl-l6-sulfanone
InChIKey: JUSYNSOYFIIJQX-LUGTWXOSSA-N
SMILES: O(C1=NC=2C(N1)=CC(Cl)=C(N2)C3=CC=C(C=C3)C4=CC=C(N=S(C)(C)=O)C=C4)[C@H]5[C@@]6([C@](OC5)([C@H](O)CO6)[H])[H]
Biological Activity: BI-9774 is a 5' AMP-activated protein kinase (AMPK) activator (IC50=12--88 nM). BI-9774 is promising for research of metabolic disorders (type 2 diabetes, obesity) and cardiovascular diseases (myocardial ischemia, heart failure)[1].
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BI-9774 | BI-9774 is a 5' AMP-activated protein kinase (AMPK) activator (IC50=12--88 nM). BI-9774 is promising for research of metabolic disorders (type 2 diabetes, obesity) and cardiovascular diseases (myocardial ischemia, heart failure). | |||||||||||||||||||||
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Keywords
