164789-02-0
164789-02-0
Chemical Structure
KAT-IN-2
- CAS No.: 164789-02-0
- Formula:C10H11ClN2O3
- Molecular Weight:242.66
InChIKey: VCCXKKFHLAJBJJ-UHFFFAOYSA-N
SMILES: O=C(C(CC(C1=CC(Cl)=CC=C1N)=O)N)O
Biological Activity: KAT-IN-2 (7) is a potent and selective kynurenine aminotransferase II (KATII) inhibitor[1][2].
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KAT-IN-2 | KAT-IN-2 (7) is a potent and selective kynurenine aminotransferase II (KATII) inhibitor. | |||||||||||||||||||||
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References
- [1]. Roberto Pellicciari, et al. Modulators of the kynurenine pathway of tryptophan metabolism: synthesis and preliminary biological evaluation of (S)-4-(ethylsulfonyl)benzoylalanine, a potent and selective kynurenine aminotransferase II (KAT II) inhibitor. ChemMedChem. 2006 May;1(5):528-31. [Content Brief]
- [2]. M Varasi, et al. Derivatives of kynurenine as inhibitors of rat brain kynurenine aminotransferase. European Journal of Medicinal Chemistry. Volume 31, Issue 1, 1996, Pages 11-21.
Keywords
