172666-82-9
Chemical Structure
Dnp-RPLALWRS
- CAS No.: 172666-82-9
- Formula:C52H77N17O14
- Molecular Weight:1164.27
InChIKey: QGUMMYMULJJAFN-VMTJQXTBSA-N
SMILES: OC[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H]3N(C([C@H](CCCNC(N)=N)NC4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O)=O)CCC3)=O)=O)=O)=O)=O)=O
Biological Activity: Dnp-RPLALWRS is a fluorescent peptide substrate designed for human matrilysin (MMP-7). After enzymatic cleavage of Dnp-RPLALWRS at the alanine-leucine bond, the release of the Dnp group alleviates fluorescence quenching, thereby enabling real-time quantitative analysis of MMP-7 activity by increasing tryptophan emission. Dnp-RPLALWRS provides a sensitive and efficient detection method for kinetic studies and inhibitor screenin[1].
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Dnp-RPLALWRS | Dnp-RPLALWRS is a fluorescent peptide substrate designed for human matrilysin (MMP-7). After enzymatic cleavage of Dnp-RPLALWRS at the alanine-leucine bond, the release of the Dnp group alleviates fluorescence quenching, thereby enabling real-time quantitative analysis of MMP-7 activity by increasing tryptophan emission. Dnp-RPLALWRS provides a sensitive and efficient detection method for kinetic studies and inhibitor screenin. | |||||||||||||||||||||
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