174630-04-7
174630-04-7
Chemical Structure
Reversin 121
- CAS No.: 174630-04-7
- Formula:C34H47N3O9
- Molecular Weight:641.75
IUPAC Name: tert-butyl N2-((S)-4-(benzyloxy)-2-((tert-butoxycarbonyl)amino)-4-oxobutanoyl)-N6-((benzyloxy)carbonyl)-L-lysinate
InChIKey: SVNKEDMVAQBLLN-SVBPBHIXSA-N
SMILES: O=C(NCCCC[C@@H](C(OC(C)(C)C)=O)NC([C@@H](NC(OC(C)(C)C)=O)CC(OCC1=CC=CC=C1)=O)=O)OCC2=CC=CC=C2
Biological Activity: Reversin 121 is a P-glycoprotein inhibitor. Reversin 121 increases the ATPase activity of MDR1. Reversin 121 reverses P-glycoprotein-mediated multidrug resistance. Reversin 121 can be used in the research of cancers[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Reversin 121 | 99.08% | Reversin 121 is a P-glycoprotein inhibitor. Reversin 121 increases the ATPase activity of MDR1. Reversin 121 reverses P-glycoprotein-mediated multidrug resistance. Reversin 121 can be used in the research of cancers. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Hoffmann K, et al. Effects of the high-affinity Peptide reversin 121 on multidrug resistance proteins in experimental pancreatic cancer. Tumour Biol. 2008;29(6):351-8. [Content Brief]
- [2]. Yabuki N, et al. Gene amplification and expression in lung cancer cells with acquired paclitaxel resistance. Cancer Genet Cytogenet. 2007 Feb;173(1):1-9. [Content Brief]
