175519-16-1
Chemical Structure
Voreloxin Hydrochloride
Synonym(s): SNS-595 Hydrochloride; Vosaroxin Hydrochloride; AG 7352 Hydrochloride
- CAS No.: 175519-16-1
- Formula:C18H20ClN5O4S
- Molecular Weight:437.90
IUPAC Name: 7-((3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl)-4-oxo-1-(thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid hydrochloride
InChIKey: JJZCCQHWCOXGCL-QNTKWALQSA-N
SMILES: [H]Cl.O=C(C1=CN(C2=NC=CS2)C3=C(C=CC(N4C[C@H](OC)[C@@H](NC)C4)=N3)C1=O)O
Biological Activity: Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
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Voreloxin Hydrochloride | 99.73% | Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. | ||||||||||||||||||||
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Keywords
