1782532-29-9
1782532-29-9
Chemical Structure
DBM 1285 dihydrochloride
- CAS No.: 1782532-29-9
- Formula:C21H24Cl2FN5S
- Molecular Weight:468.42
IUPAC Name: N-cyclopropyl-4-(4-(4-fluorophenyl)-2-(piperidin-4-yl)thiazol-5-yl)pyrimidin-2-amine dihydrochloride
InChIKey: ANQWETXPBPZVOF-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=C(SC(C3CCNCC3)=N2)C4=CC=NC(NC5CC5)=N4)C=C1.Cl.Cl
Biological Activity: DBM 1285 dihydrochloride is an orally active TNF-α production inhibitor with anti-inflammatory effects. DBM 1285 dihydrochloride inhibits Lipopolysaccharide (LPS)-induced TNF-α secretion in various cells of macrophage/monocyte lineage[1].
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DBM 1285 dihydrochloride | DBM 1285 dihydrochloride is an orally active TNF-α production inhibitor with anti-inflammatory effects. DBM 1285 dihydrochloride inhibits Lipopolysaccharide (LPS)-induced TNF-α secretion in various cells of macrophage/monocyte lineage. | |||||||||||||||||||||
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