179815-06-6
179815-06-6
Chemical Structure
EBNA3B 399-408
- CAS. Nr.: 179815-06-6
- Formula:C49H81N15O16
- Molecular Weight:1136.26
InChIKey: ZTFDIFPFWOYKBK-HSOKPKQBSA-N
SMILES: O=C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
Biological Activity: EBNA3B 399-408 is an immunodominant HLA-A11-restricted cytotoxic T-lymphocyte epitope in EBNA3B. EBNA3B 399-408 can be used in the research of EBV infection, empyema-associated lymphoma, and nasal natural killer cell lymphoma[1][2][3][4].
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EBNA3B 399-408 | EBNA3B 399-408 is an immunodominant HLA-A11-restricted cytotoxic T-lymphocyte epitope in EBNA3B. EBNA3B 399-408 can be used in the research of EBV infection, empyema-associated lymphoma, and nasal natural killer cell lymphoma. | |||||||||||||||||||||
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References
- [1]. Chu PG, et al. Epstein-Barr virus (EBV) nuclear antigen (EBNA)-4 mutation in EBV-associated malignancies in three different populations. Am J Pathol. 1999;155(3):941-947. [Content Brief]
- [2]. Tan LC, et al. A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers. J Immunol. 1999 Feb 1;162(3):1827-35. [Content Brief]
- [3]. Kanno H, et al. Sequences of cytotoxic T-lymphocyte epitopes in the Epstein-Barr virus (EBV) nuclear antigen-3B gene in a Japanese population with or without EBV-positive lymphoid malignancies. Int J Cancer. 2000;88(4):626-632. [Content Brief]
- [4]. Sawada A, et al. Epstein-Barr virus latent gene sequences as geographical markers of viral origin: unique EBNA3 gene signatures identify Japanese viruses as distinct members of the Asian virus family. J Gen Virol. 2011 May;92(Pt 5):1032-1043. [Content Brief]
