1799506-31-2
Chemical Structure
(R,S,R)-AHPC-NHBoc
- CAS No.: 1799506-31-2
- Formula:C27H38N4O5S
- Molecular Weight:530.68
IUPAC Name: tert-butyl ((R)-1-((2R,4S)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate
InChIKey: PKNFPFFOAWITLF-VWPQPMDRSA-N
SMILES: C([C@H](NC(OC(C)(C)C)=O)[C@](C)(C)C)(=O)N1[C@@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](O)C1
Biological Activity: (R,S,R)-AHPC-NHBoc is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (R,S,R)-AHPC-NHBoc can be linked to a target protein ligand via a linker to form a PROTAC.
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(R,S,R)-AHPC-NHBoc | (R,S,R)-AHPC-NHBoc is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (R,S,R)-AHPC-NHBoc can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords