1802937-26-3
1802937-26-3
Chemical Structure
JP-153
- CAS No.: 1802937-26-3
- Formula:C21H19NO5
- Molecular Weight:365.38
IUPAC Name: 4-(3,4,5-trimethoxyphenyl)-1,4-dihydro-2H-naphtho[1,2-d][1,3]oxazin-2-one
InChIKey: NIDMIFDHMDRHLS-UHFFFAOYSA-N
SMILES: O=C1OC(C2=CC(OC)=C(OC)C(OC)=C2)C3=CC=C4C=CC=CC4=C3N1
Biological Activity: JP-153 is the Src-FAK-Paxillin signaling inhibitor. JP-153 inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473). JP-153 reduces VEGF-induced migration and proliferation in retinal endothelial cells. JP-153 can be uesd for the study of neovascular eye disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JP-153 | 99.45% | JP-153 is the Src-FAK-Paxillin signaling inhibitor. JP-153 inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473). JP-153 reduces VEGF-induced migration and proliferation in retinal endothelial cells. JP-153 can be uesd for the study of neovascular eye disease. | ||||||||||||||||||||
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