1809420-71-0
Chemical Structure
Resomelagon
Synonym(s): AP1189
- CAS No.: 1809420-71-0
- Formula:C14H14N6O2
- Molecular Weight:298.30
IUPAC Name: (E)-2-((E)-3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidene)hydrazine-1-carboximidamide
InChIKey: ZSDGHWLLLGYAJV-AHEHSYJASA-N
SMILES: N=C(N)N/N=C/C=C/C1=CC=CN1C2=C(C=CC=C2)[N+]([O-])=O
Biological Activity: Resomelagon (AP1189) is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon has anti-inflammatory activity. Resomelagon can be used for obesity and chronic inflammation research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Resomelagon | 98.79% | Resomelagon (AP1189) is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon has anti-inflammatory activity. Resomelagon can be used for obesity and chronic inflammation research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Montero-Melendez T, et, al. Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol. 2015 Apr 1;194(7):3381-8. [Content Brief]
- [2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical
Keywords
