1810092-90-0
1810092-90-0
Chemical Structure
N-Benzyl-N-demethylpronqodine A
- CAS No.: 1810092-90-0
- Formula:C14H10N2O2S
- Molecular Weight:270.31
SMILES: O=C(C(NCC1=CC=CC=C1)=C2)C3=C(SN=C3)C2=O
Biological Activity: N-Benzyl-N-demethylpronqodine A (Compound 16) is an inhibitor of NAD(P)H:quinine acceptor oxidoreductase 1 (NQO1) with an IC50 of 83.3 nM[1].
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N-Benzyl-N-demethylpronqodine A | N-Benzyl-N-demethylpronqodine A (Compound 16) is an inhibitor of NAD(P)H:quinine acceptor oxidoreductase 1 (NQO1) with an IC50 of 83.3 nM. | |||||||||||||||||||||
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References
- [1]. Blunt CE, et al., Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity. Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8740-5. doi: 10.1002/anie.201503323. Epub 2015 Jun 10. PMID: 26096359. [Content Brief]
Keywords
