1824664-89-2
Chemical Structure
Anizatrectinib
Synonym(s): hTrkA-IN-1
- CAS No.: 1824664-89-2
- Formula:C29H32FN7O2
- Molecular Weight:529.61
IUPAC Name: 1-((3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1H-pyrazol-5-yl)urea
InChIKey: BGKSBHPSVMJTFL-IZZNHLLZSA-N
SMILES: O=C(NC1=C(C)C(C2=CN=C(C)N=C2)=NN1C3=CC=CC=C3)N[C@@H]4CN(CCOC)C[C@H]4C5=CC=CC(F)=C5
Biological Activity: Anizatrectinib (hTrkA-IN-1) is an orally active and blood-brain barrier-penetrant TrkA kinase/hERG channel inhibitor. Anizatrectinib can be used for research on TrkA-mediated related diseases, such as pain, cancer, inflammation, and inflammatory diseases[1].
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Anizatrectinib | Anizatrectinib (hTrkA-IN-1) is an orally active and blood-brain barrier-penetrant TrkA kinase/hERG channel inhibitor. Anizatrectinib can be used for research on TrkA-mediated related diseases, such as pain, cancer, inflammation, and inflammatory diseases. | |||||||||||||||||||||
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