1858275-91-8
1858275-91-8
Chemical Structure
ML-93
- CAS No.: 1858275-91-8
- Formula:C25H27ClN4O6S2
- Molecular Weight:579.09
InChIKey: HKIARJIHQHADQP-XAVKYBOGSA-N
SMILES: CC1=C(C=C(S1)C(C2=CN=CN=C2N[C@@H]3C[C@@H]([C@H](C3)O)COS(N)(=O)=O)=O)[C@H]4C5=CC(Cl)=CC=C5CCO4
Biological Activity: ML-93 is an orally active SAE inhibitor, with an IC50 value of 0.4 μM. ML-93 inhibits the SUMOylation pathway in HCT116 cells. ML-93 shows robust antitumor activity in the HCT116 colorectal carcinoma xenograft model. ML-93 can be used for the study of colorectal cancer[1].
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ML-93 | ML-93 is an orally active SAE inhibitor, with an IC50 value of 0.4 μM. ML-93 inhibits the SUMOylation pathway in HCT116 cells. ML-93 shows robust antitumor activity in the HCT116 colorectal carcinoma xenograft model. ML-93 can be used for the study of colorectal cancer. | |||||||||||||||||||||
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References
Keywords
