186643-40-3
Chemical Structure
KF 22678
- CAS No.: 186643-40-3
- Formula:C32H38N2O10S3
- Molecular Weight:706.85
IUPAC Name: S-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl) (2R)-2-((12Z,35R,2R,6Z,8R,10E,12Z)-2,6-dimethyl-31-oxido-33,9-dioxo-8-(((R)-tetrahydro-2H-pyran-2-yl)oxy)-1(2,4)-thiazola-3(2,5)-isothiazolidinacyclotridecaphane-6,10,12-trien-35-yl)-2-hydroxypropanethioate
InChIKey: ATFISCUSRDIBNV-XKPIYFQGSA-N
SMILES: CC1=C(OC(O1)=O)CSC([C@](O)([C@@]2(C3)S(N([C@@H](C4=NC(/C=C\C=C\C([C@H](O[C@]5([H])CCCCO5)/C=C(C)\CC2)=O)=CS4)C)C3=O)=O)C)=O
Biological Activity: KF 22678 is a thioester derivative of leinamycin. KF 22678 exhibits a broad antitumor spectrum against human carcinoma xenografts, including lung, colon, ovary, and prostate cancers. KF 22678 can be used for the study of cancer[1].
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KF 22678 | KF 22678 is a thioester derivative of leinamycin. KF 22678 exhibits a broad antitumor spectrum against human carcinoma xenografts, including lung, colon, ovary, and prostate cancers. KF 22678 can be used for the study of cancer. | |||||||||||||||||||||
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