1881244-28-5
Chemical Structure
MGL-IN-1
- CAS No.: 1881244-28-5
- Formula:C24H22FN5O4
- Molecular Weight:463.46
IUPAC Name: (3R,4S)-1-(1-(1H-1,2,4-triazole-1-carbonyl)piperidin-4-yl)-4-(benzo[d][1,3]dioxol-5-yl)-3-(4-fluorophenyl)azetidin-2-one
InChIKey: XRIROGBLGLPXQI-FGZHOGPDSA-N
SMILES: O=C1N(C(CC2)CCN2C(N3C=NC=N3)=O)[C@@](C4=CC=C5C(OCO5)=C4)([H])[C@@]1([H])C(C=C6)=CC=C6F
Biological Activity: MGL-IN-1 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. MGL-IN-1 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. MGL-IN-1 displays high membrane permeability and brain penetrant[1].
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MGL-IN-1 | 99.21% | MGL-IN-1 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. MGL-IN-1 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. MGL-IN-1 displays high membrane permeability and brain penetrant. | ||||||||||||||||||||
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Keywords