1884577-99-4
1884577-99-4
Chemical Structure
Boc-Val-Ala-PAB
- CAS No.: 1884577-99-4
- Formula:C20H31N3O5
- Molecular Weight:393.48
IUPAC Name: tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
InChIKey: AWZITSKTOAURSJ-BBRMVZONSA-N
SMILES: O=C(N[C@@H](C)C(NC(C=C1)=CC=C1CO)=O)[C@H](C(C)C)NC(OC(C)(C)C)=O
Biological Activity: Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Boc-Val-Ala-PAB | 99.98% | Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs). | ||||||||||||||||||||
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References
- [1]. HP Wilson, et al. Pyrrolobenzodiazepines and conjugates thereof: World Intellectual Property Organization, WO2016037644. 2016-03-17.
- [2]. HP Wilson, et al. Preparation of pyrrolobenzodiazepine dimers and their conjugates with cell binding agents, especially pyrrolobenzodiazepine dimer drug linker antibody conjugates and their use for treating proliferative diseases, particularly cancer: World Intellectual Property Organization, WO2016038383. 2016-03-17
Keywords
