2027497-52-3
2027497-52-3
Chemical Structure
RGH-706
- CAS No.: 2027497-52-3
- Formula:C26H27ClN4O2
- Molecular Weight:462.97
InChIKey: GETWVXLVCKQZME-UHFFFAOYSA-N
SMILES: O=C1C=C(OCC2=NC=C(Cl)C=C2)C=CN1C3=CC4=C(N(CCN(C(C)C)CC5)C5=C4)C=C3
Biological Activity: RGH-706 is an orally active, blood-brain barrier-permeable, selective MCH1 receptor antagonist with an IC50 of 6.2 nM against hMCHR1. RGH-706 shows no antagonistic activity against hMCH2 receptors. RGH-706 improves obesity. RGH-706 can be used in research related to obesity and Prader-Willi syndrome[1].
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RGH-706 | RGH-706 is an orally active, blood-brain barrier-permeable, selective MCH1 receptor antagonist with an IC50 of 6.2 nM against hMCHR1. RGH-706 shows no antagonistic activity against hMCH2 receptors. RGH-706 improves obesity. RGH-706 can be used in research related to obesity and Prader-Willi syndrome. | |||||||||||||||||||||
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