2032282-97-4
2032282-97-4
Chemical Structure
Rbin-2
- CAS No.: 2032282-97-4
- Formula:C13H11BrN4S
- Molecular Weight:335.22
IUPAC Name: 7-bromo-3-((2-methylallyl)thio)-5H-[1,2,4]triazino[5,6-b]indole
InChIKey: OVDAOBDZJJZJMY-UHFFFAOYSA-N
SMILES: C=C(C)CSC1=NN=C2C(NC3=C2C=CC(Br)=C3)=N1
Biological Activity: Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1].
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Rbin-2 | 98.0% | Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly. | ||||||||||||||||||||
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References
Keywords
