2036123-97-2
Chemical Structure
Antifungal agent 34
- CAS No.: 2036123-97-2
- Formula:C46H40F3N3O3
- Molecular Weight:739.82
IUPAC Name: (3S,3'R,4'R,5'S)-5'-benzyl-5''-((E)-4-methylbenzylidene)-1''-((E)-styryl)-4'-(p-tolyl)-5-(trifluoromethoxy)dispiro[indoline-3,2'-pyrrolidine-3',3''-piperidine]-2,4''-dione
InChIKey: GQKJSHSHGXNXCH-PJRRGKTFSA-N
SMILES: O=C1[C@]2(C3=CC(OC(F)(F)F)=CC=C3N1)[C@@]4(C(/C(CN(C4)/C=C/C5=CC=CC=C5)=C/C6=CC=C(C=C6)C)=O)[C@@H](C7=CC=C(C=C7)C)[C@@H](N2)CC8=CC=CC=C8
Biological Activity: Antifungal agent 34 (compound 6i) is a potent antifungal agent. Antifungal agent 34 shows a potent antifungal activity against Candida albicans, with a MIC of 4 µg/mL. Antifungal agent 34 shows significant inhibition on Candida albicans hyphae and biofilm development. Antifungal agent 34 exhibits no cytotoxicity to mammalian cells[1].
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Antifungal agent 34 | Antifungal agent 34 (compound 6i) is a potent antifungal agent. Antifungal agent 34 shows a potent antifungal activity against Candida albicans, with a MIC of 4 µg/mL. Antifungal agent 34 shows significant inhibition on Candida albicans hyphae and biofilm development. Antifungal agent 34 exhibits no cytotoxicity to mammalian cells. | |||||||||||||||||||||
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Keywords
