2055041-40-0
Chemical Structure
Azide-PEG1-Val-Cit-PABC-OH
- CAS No.: 2055041-40-0
- Formula:C23H36N8O6
- Molecular Weight:520.58
IUPAC Name: (S)-2-((R)-2-(3-(2-azidoethoxy)propanamido)-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide
InChIKey: BDMOXMNQSIHXBI-AZUAARDMSA-N
SMILES: OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@@H](C(C)C)NC(CCOCCN=[N+]=[N-])=O)=O)=O
Biological Activity: Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azide-PEG1-Val-Cit-PABC-OH | Azide-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azide-PEG1-Val-Cit-PABC-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
