2057420-00-3
2057420-00-3
Chemical Structure
BRD7539
- CAS No.: 2057420-00-3
- Formula:C23H22FN3O2
- Molecular Weight:391.44
IUPAC Name: (2S,3S,4S)-2-cyano-3-(4-((3-fluorophenyl)ethynyl)phenyl)-4-(hydroxymethyl)-N-propylazetidine-1-carboxamide
InChIKey: DECVPFAWLCQCPS-VSKRKVRLSA-N
SMILES: N#C[C@@H]1[C@H](C2=CC=C(C=C2)C#CC3=CC(F)=CC=C3)[C@H](N1C(NCCC)=O)CO
Biological Activity: BRD7539 is a PfDHODH inhibitor (IC50 = 0.033 μM). BRD7539 has potent activity against both multidrug-resistant asexual blood-stage (P. falciparum, Dd2 strain, EC50 = 0.010 μM) and liver-stage (P. berghei, EC50 = 0.015 μM) parasites[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BRD7539 | BRD7539 is a PfDHODH inhibitor (IC50 = 0.033 μM). BRD7539 has potent activity against both multidrug-resistant asexual blood-stage (P. falciparum, Dd2 strain, EC50 = 0.010 μM) and liver-stage (P. berghei, EC50 = 0.015 μM) parasites. | |||||||||||||||||||||
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