2070014-88-7
2070014-88-7
Chemical Structure
SRI-011381 hydrochloride
- CAS No.: 2070014-88-7
- Formula:C20H32ClN3O
- Molecular Weight:365.94
IUPAC Name: 1-benzyl-3-cyclohexyl-1-(piperidin-4-ylmethyl)urea hydrochloride
InChIKey: GPNMJVSGNMDOJN-UHFFFAOYSA-N
SMILES: O=C(NC1CCCCC1)N(CC2=CC=CC=C2)CC3CCNCC3.Cl[H]
Biological Activity: SRI-011381 hydrochloride is an orally active TGF-β signaling agonist, exhibits neuroprotective effects, with blood-brain barrier permeability[1][2][3].
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SRI-011381 hydrochloride | 99.94% | SRI-011381 hydrochloride is an orally active TGF-β signaling agonist, exhibits neuroprotective effects, with blood-brain barrier permeability. | ||||||||||||||||||||
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SRI-011381 hydrochloride (Standard) | ≥98% | SRI-011381 (hydrochloride) (Standard) is the analytical standard of SRI-011381 (hydrochloride) (HY-100347A). This product is intended for research and analytical applications. SRI-011381 hydrochloride is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. | ||||||||||||||||||||
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References
- [1]. Jingyin Han, et al. The Improvement Effect of Sodium Ferulate on the Formation of Pulmonary Fibrosis in Silicosis Mice Through the Neutrophil Alkaline Phosphatase 3 (NALP3)/Transforming Growth Factor-β1 (TGF-β1)/α-Smooth Muscle Actin (α-SMA) Pathway. Med Sci Monit. 2021 Jun 15;27:e927978. [Content Brief]
- [2]. Qian Wu, et al. Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling. Theranostics. 2021 Jul 25;11(17):8480-8499. [Content Brief]
- [3]. Luo J. TGF-β as a Key Modulator of Astrocyte Reactivity: Disease Relevance and Therapeutic Implications. Biomedicines. 2022 May 23;10(5):1206. [Content Brief]
