2083630-26-4
2083630-26-4
Chemical Structure
PS432
- CAS No.: 2083630-26-4
- Formula:C25H19ClN2O5S
- Molecular Weight:494.95
IUPAC Name: ethyl 2-(5-(4-chlorophenyl)furan-2-yl)-4-hydroxy-1-(6-methylbenzo[d]thiazol-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate
InChIKey: NBZPOMWJBSLLCT-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C(N(C2=NC3=CC=C(C)C=C3S2)C1C4=CC=C(C5=CC=C(Cl)C=C5)O4)=O)OCC
Biological Activity: PS432 is a PKC inhibitor with IC50s of 16.9 μM (PKCι) and 18.5 μM (PKCζ), respectively. PS432 effectively inhibits the proliferation of non-small cell lung cancer cells (NSCLCs) and tumor growth in mouse xenograft models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PS432 | 99.9% | PS432 is a PKC inhibitor with IC50s of 16.9 μM (PKCι) and 18.5 μM (PKCζ), respectively. PS432 effectively inhibits the proliferation of non-small cell lung cancer cells (NSCLCs) and tumor growth in mouse xenograft models. | ||||||||||||||||||||
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References
Keywords
