2088281-24-5
Chemical Structure
CAQK peptide
- CAS No.: 2088281-24-5
- Formula:C17H32N6O6S
- Molecular Weight:448.54
InChIKey: XOEMOWBIULLVPI-BJDJZHNGSA-N
SMILES: O=C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(O)=O)=O)=O)[C@H](CS)N
Biological Activity: CAQK peptide selectively binds to injured mouse brain. CAQK peptide selectively targets demyelinating areas and it is absent from healthy tissue. The CAQK peptide target is a proteoglycan complex upregulated in brain injuries and is used for drug delivery. CAQK peptide can penetrate the blood-brain barrier[1][2].
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CAQK peptide | 98.15% | CAQK peptide selectively binds to injured mouse brain. CAQK peptide selectively targets demyelinating areas and it is absent from healthy tissue. The CAQK peptide target is a proteoglycan complex upregulated in brain injuries and is used for drug delivery. CAQK peptide can penetrate the blood-brain barrier. | ||||||||||||||||||||
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- [1]. Charly Abi-Ghanem, et al. CAQK, a peptide associating with extracellular matrix components targets sites of demyelinating injuries. Front Cell Neurosci. 2022 Aug 22:16:908401. [Content Brief]
- [2]. Aman P Mann, et al. A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries. Nat Commun. 2016 Jun 28:7:11980. [Content Brief]
Keywords