2095286-57-8
2095286-57-8
Chemical Structure
YVPGP
- CAS. Nr.: 2095286-57-8
- Formula:C26H37N5O7
- Molecular Weight:531.60
InChIKey: ODXFAMVHVQBPTQ-XWUOBKMESA-N
SMILES: O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(NCC(N2[C@@H](CCC2)C(O)=O)=O)=O)=O)[C@H](CC3=CC=C(C=C3)O)N
Biological Activity: YVPGP is an oligopeptide exacted from Anthopleura anjunae. YVPGP has a significant antitumor activity by mediating PI3K/AKT/mTOR signaling pathway. YVPGP arrests DU-145 cells in the S phase and induces apoptosis via mitochondrial and death receptor pathways (caspase3, 7, 8, 9). YVPGP effectively inhibits tumor growth in DU-145 xenografts mice model, promising for prostate cancer research[1].
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YVPGP | YVPGP is an oligopeptide exacted from Anthopleura anjunae. YVPGP has a significant antitumor activity by mediating PI3K/AKT/mTOR signaling pathway. YVPGP arrests DU-145 cells in the S phase and induces apoptosis via mitochondrial and death receptor pathways (caspase3, 7, 8, 9). YVPGP effectively inhibits tumor growth in DU-145 xenografts mice model, promising for prostate cancer research. | |||||||||||||||||||||
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