2095417-47-1
Chemical Structure
5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine
- CAS No.: 2095417-47-1
- Formula:C35H34N2O9
- Molecular Weight:626.65
IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-(furan-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: HTMVCWPFTLMWRP-WTGZKXAYSA-N
SMILES: O=C(C(C1=CC=CO1)=CN2[C@H]3[C@H](OC)[C@H](O)[C@@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)O3)NC2=O
Biological Activity: 5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine | 5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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