2102414-23-1
Chemical Structure
KP-6
- CAS No.: 2102414-23-1
- Formula:C159H232N46O44
- Molecular Weight:3491.83
SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H]2N(CCC2)C([C@@H](N)CCC(N)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)CC8=CC=C(C=C8)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC9=CNC%10=CC=CC=C9%10)=O)=O
Biological Activity: KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD)[1].
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KP-6 | KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD). | |||||||||||||||||||||
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Keywords
