211120-62-6
211120-62-6
Chemical Structure
Ro 48-8587
- CAS No.: 211120-62-6
- Formula:C12H7N7O4
- Molecular Weight:313.23
IUPAC Name: 9-(1H-imidazol-1-yl)-8-nitro-[1,2,4]triazolo[1,5-c]quinazoline-2,5(3H,6H)-dione
InChIKey: AVTCDZCFLPMWQN-UHFFFAOYSA-N
SMILES: O=C1NN2C(NC3=C(C=C(N4C=CN=C4)C([N+]([O-])=O)=C3)C2=N1)=O
Biological Activity: Ro 48-8587 is a selective AMPA receptor antagonist with an IC50 of 8 nM. Ro 48-8587 functionally inhibits AMPA receptor activity, blocks AMPA-induced depolarization of rat cortical wedges. Ro 48-8587 can be used for the research of ischaemia and seizures[1].
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Ro 48-8587 | Ro 48-8587 is a selective AMPA receptor antagonist with an IC50 of 8 nM. Ro 48-8587 functionally inhibits AMPA receptor activity, blocks AMPA-induced depolarization of rat cortical wedges. Ro 48-8587 can be used for the research of ischaemia and seizures. | |||||||||||||||||||||
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