2112731-51-6
Chemical Structure
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester
- CAS No.: 2112731-51-6
- Formula:C26H45N5O12
- Molecular Weight:619.66
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 1-azido-12-(tert-butoxycarbonyl)-3,6,9,15,18,21-hexaoxa-12-azatetracosan-24-oate
InChIKey: KGZHKOJBRRUXFU-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
Biological Activity: N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(Azido-PEG3)-N-Boc-PEG3-NHS ester | N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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