2133321-59-0
2133321-59-0
Chemical Structure
PROTAC HTT Degrader-1
- CAS No.: 2133321-59-0
- Formula:C36H47N5O5S
- Molecular Weight:661.85
InChIKey: OILBTTNZPXJVJN-QBACOJCQSA-N
SMILES: O=C(N[C@@H](CC(C)C)C(NCCOCCOCCNC(C=C1)=CC=C1C2=NC3=CC=C(C)C=C3S2)=O)[C@@H](O)[C@H](N)CC4=CC=CC=C4
Biological Activity: PROTAC HTT Degrader-1 is a cIAP1-recruiting Htt PROTAC degrader. PROTAC HTT Degrader-1 recruits cIAP1 to mHtt or wtHtt and induces their degradation via the ubiquitin-proteasome system. PROTAC HTT Degrader-1 can be used in research related to Huntington's disease[1].
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PROTAC HTT Degrader-1 | PROTAC HTT Degrader-1 is a cIAP1-recruiting Htt PROTAC degrader. PROTAC HTT Degrader-1 recruits cIAP1 to mHtt or wtHtt and induces their degradation via the ubiquitin-proteasome system. PROTAC HTT Degrader-1 can be used in research related to Huntington's disease. | |||||||||||||||||||||
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References
Keywords
