21489-20-3
21489-20-3
Chemical Structure
Talsupram
- CAS No.: 21489-20-3
- Formula:C20H25NS
- Molecular Weight:311.48
IUPAC Name: 2-amino-2-(4-bromo-2-fluorophenyl)ethan-1-ol
InChIKey: FKHYYOUFMJBLAF-UHFFFAOYSA-N
SMILES: CC1(C)C2=C(C=CC=C2)C(C3=CC=CC=C3)(CCCNC)S1
Biological Activity: Talsupram is a selective noradrenaline inhibitor that has a high affinity for the noradrenaline transporter. Talsupram exhibits anti-hyperalgesic effects. Talsupram can decrease ethanol intake to the levels prior to REM-induced deprivation in rat model[1][2].
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Talsupram | Talsupram is a selective noradrenaline inhibitor that has a high affinity for the noradrenaline transporter. Talsupram exhibits anti-hyperalgesic effects. Talsupram can decrease ethanol intake to the levels prior to REM-induced deprivation in rat model. | |||||||||||||||||||||
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References
- [1]. Hacısüleyman, L., et al., (2022). Analgesic Effects of Vilazodone, Indatraline, and Talsupram in a Rat Model of Neuropathic Pain. Turkish journal of pharmaceutical sciences, 19(3), 336–342. [Content Brief]
- [2]. Aalto, J., & Kiianmaa, K. (1986). REM-sleep deprivation-induced increase in ethanol intake: role of brain monoaminergic neurons. Alcohol (Fayetteville, N.Y.), 3(6), 377–381. [Content Brief]
