2166616-75-5
2166616-75-5
Chemical Structure
LY-3381916
Synonym(s): IDO1-IN-5
- CAS No.: 2166616-75-5
- Formula:C23H25FN2O3
- Molecular Weight:396.45
IUPAC Name: (R)-4-fluoro-N-(1-(1-(tetrahydro-2H-pyran-4-carbonyl)indolin-5-yl)ethyl)benzamide
InChIKey: NUBWFWVVKLRSHS-OAHLLOKOSA-N
SMILES: FC1=CC=C(C(N[C@H](C)C2=CC=C(N(C(C3CCOCC3)=O)CC4)C4=C2)=O)C=C1
Biological Activity: LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
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LY-3381916 | 99.92% | LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. | ||||||||||||||||||||
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LY-3381916 (Standard) | ≥98% | LY-3381916 (Standard) is the analytical standard of LY-3381916 (HY-111540). This product is intended for research and analytical applications. LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacKing heme rather than mature heme-bound IDO1. | ||||||||||||||||||||
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