2169223-48-5

JAB-3068 Chemical Structure
2169223-48-5

Chemical Structure

JAB-3068

Synonym(s): SHP2-IN-6

  • CAS 番号: 2169223-48-5
  • Formula:C22H26F2N6O2S
  • Molecular Weight:476.54

IUPAC Name: (S)-1-(4-((3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl)thio)-3,3-difluoroindolin-1-yl)ethan-1-one

InChIKey: HGYTYZKWKUXRKA-MRXNPFEDSA-N

SMILES: CC(N1CC(F)(F)C2=C1C=CC=C2SC3=NC=C(N(CC4)CCC54[C@H](N)COC5)N=C3N)=O

Biological Activity: JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM[1].

製品番号 製品名 純度 製品説明 Pricing
HY-131132
JAB-3068 99.49% JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM.
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