2172820-07-2
2172820-07-2
Chemical Structure
VH032 amide-PEG1-acid
- CAS No.: 2172820-07-2
- Formula:C28H38N4O7S
- Molecular Weight:574.69
IUPAC Name: 3-(3-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)propanoic acid
InChIKey: HVPZHRHEHKZOOJ-TYBLODHISA-N
SMILES: O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCC(O)=O)=O)=O)C[C@H](O)C3
Biological Activity: VH032 amide-PEG1-acid (Linker 10) is an E3 ligase ligand-linker conjugate comprising an E3 ligase ligand and a PEG1 linker terminated with a carboxylic acid group. VH032 amide-PEG1-acid can be used for the synthesis of CDK4/6-targeting PROTACs[1].
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VH032 amide-PEG1-acid | 97.12% | VH032 amide-PEG1-acid (Linker 10) is an E3 ligase ligand-linker conjugate comprising an E3 ligase ligand and a PEG1 linker terminated with a carboxylic acid group. VH032 amide-PEG1-acid can be used for the synthesis of CDK4/6-targeting PROTACs. | ||||||||||||||||||||
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