2229725-98-6
Chemical Structure
Thalidomide-pinacolborane
- CAS No.: 2229725-98-6
- Formula:C19H21BN2O6
- Molecular Weight:384.19
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-1,3-dione
InChIKey: HXUIXDCRHZHRBJ-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(B4OC(C)(C)C(C)(C)O4)=C3)=O
Biological Activity: Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
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Thalidomide-pinacolborane | 97.0% | Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction. | ||||||||||||||||||||
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Keywords
