2229974-83-6

XY028-140 Chemical Structure
2229974-83-6

Chemical Structure

XY028-140

  • CAS No.: 2229974-83-6
  • Formula:C39H40N10O7
  • Molecular Weight:760.80

IUPAC Name: 4-((2-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

InChIKey: IWFNIKIERKCKFZ-UHFFFAOYSA-N

SMILES: O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(NCC(N4CCN(CC4)C5=CN=C(NC6=NC(N(C7CCCC7)C(C(C(C)=O)=C8C)=O)=C8C=N6)C=C5)=O)=CC=C2

Biological Activity: XY028-140 is a PROTAC-type degrader targeting CDK4/6, which degrades CDK4/6 by recruiting CRBN-type E3 ligase. XY028-140 can be used in CDK4/6-mediated cancer-related research[1].

Cat. No. Product Name Purity Description Pricing
HY-138946
XY028-140 98.52% XY028-140 is a PROTAC-type degrader targeting CDK4/6, which degrades CDK4/6 by recruiting CRBN-type E3 ligase. XY028-140 can be used in CDK4/6-mediated cancer-related research.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References